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As indicated above, the active form of ghrelin that induces GH secretion, by stimulating GHRH secretion and inhibiting SS and IGF-I secretion (Figure 12A), and many other physiological functions, such as inhibiting cell death in cardiac and endothelial cells [172], is the acylated form (acyl ghrelin), produced by attaching an octanoyl group to amino acid 3 (serine) carried out by ghrelin O-acyl transferase (GOAT) (Figure 12B) [173, 174]

Similarly, knowing the best foods to eat on semaglutide supports both weight loss and nutritional adequacy

doi: 10.1038/bjc.2016.147 19 Van CutsemETaberneroJLakomyRPrenenHPrausovaJMacarullaTet al