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Which brings us to our second angle of attack against DHT Angle Of Attack #2: Reducing 5-Alpha Reductase There seems to be at least two pathways to inhibiting (or reducing the presence of) this enzyme

Weight management A 2018 meta-analysis of randomized, placebo-controlled trials found that lipoic acid supplementation in those with high body mass index (BMI) resulted in significant, yet modest, reductions in weight (9 studies) and BMI (11 studies) in the absence of caloric restriction (except in one study) (105)

There are no large human trials to support the safety or effectiveness