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Cysteine levels in the supernatant were measured by a Cysteine Assay Kit (#MAK255, Sigma) and the cysteine standards

Keloid Senescent Fibroblast Elimination & SASP Suppression (Communications Biology, 2025) FOXO4-DRI Induces p53-pS15 Nuclear Exclusion and Apoptosis in Keloid Fibroblast Models A study published in Communications Biology (Nature Publishing Group, 2025) used single-cell RNA sequencing to characterise the senescent cell landscape in keloids pathological scars with tumour-like aggressiveness

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Rare but serious reactions include chest pain, irregular heartbeat, or paradoxical bronchospasm (worsening wheeze), all of which require immediate medical attention