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Homocysteine can also transform into homocysteine thiolactone in a self-loop reaction, which boosts the generation of reactive oxygen species (ROS) with the development of oxidative stress (Silla et al

A recent study showed that high expression of SLC7A11 increases the sensitivity of tumor cells to oxidative stress and promotes the growth of primary tumors (Yan et al., 2023)

As granulomas mature, they develop fibrous walls and experience a significant decrease in the number of vessels penetrating the structure, which hampers the penetration of anti-TB drugs into the necrotic and hypoxic areas of the granuloma, where M.tb persists [98, 99]

Vitamin D3 - approved for use from an early age, to prevent disorders in the development of the skeleton and muscle tissue