Um ensaio de fase II conduzido na Crocia avaliou o BPC-157 oral em pacientes com colite ulcerativa, com resultados preliminares sugerindo melhora nos escores de atividade da doena
Senolytics face critical limitations, including insufficient specificity for heterogeneous senescent cell populations, which causes off-target cytotoxicity against vital non-senescent cells (e.g., stem/progenitor cells) and potential disruption of beneficial senescence functions in tissue repair
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