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Studies have shown that the concentrations of pro-inflammatory cytokines and inflammatory markers such as C-reactive protein, interleukin-1 (IL-1), IL-6, IL-17F, and CCL8 in acutely exposed individuals at high altitudes are significantly higher than at sea level, while the concentrations of the anti-inflammatory cytokine IL-10 are significantly lower than at sea level (Song et al., 2016

[156] We stated that we will apply the same policy as prior to the FY 2020 final rule for calculating the rural floor, in which the rural wage index sets the rural floor

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