4.2.2 Antioxidant delivery nanomaterials Most antioxidants have low bioavailability due to their inherent properties (191, 192)
Some researchers have identified the main efflux transport proteins of SL was multidrug resistance-associated protein (MRP2) and breast cancer resistance protein (BCRP), and compounds that inhibited the efflux transport proteins MRP2 and BCRP could enhance the absorption and activity of SL (Xie et al., 2019), such as piperine or tangeretin (Yuan et al., 2018)
Not intended for pregnant or nursing mothers or individuals under 18. Always consult a healthcare professional before starting a new supplement regimen
SL significantly inhibited the intrahepatic synthesis of several disease-related pro-inflammatory cytokine mRNAs, i.e., for TNF, interferon-gamma (IFN-g), IL-4, and IL-2, intrahepatic induction of iNOS, and intrahepatic activation of NF-B (Morishima et al., 2010