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Natural American Spirit maker Santa Fe Natural Tobacco Company Inc

It is founded on the research that has been conducted associating AQI (PM 2.5 level) with smoking, whereby the formula below is used: Number of Cigarettes = AQI 0.05

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About a decade ago, the company made worldwide headlines when it succeeded in creating genetically engineered tobacco plants that naturally developed a considerably lower nicotine content in its leaves than conventionally farmed varieties