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Likewise, DHAR overexpression in tobacco and maize led to an increase in ascorbate and glutathione concentration, as well as a shift towards the reduced state for glutathione (Chen et al., 2003)

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Goldenseal ( Hydrastis canadensis L.) was further confirmed to be protective against AALI by inhibiting CYP2E1 in rats (Yamaura et al., 2011)