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Indeed, previous studies showed elongated and swollen mitochondria as well as fragmentation, branching and cristae depletion in primary bronchial epithelial cells (PBEC) from ex-smoking COPD patients with very severe disease compared to never-smoker controls 19 , and in PBECs from COPD patients relative to smokers without COPD 20,21,22

Furthermore, internationally there are numerous cases of accidental ingestion and other damages due to defects in the device

A high-temperature heating type device that directly heats tobacco leaves with a heater

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