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The in vivo toxicity and potential bladder carcinogenicity of menthol E-liquids is further supported by evidence that menthol E-liquid aerosols contain higher levels of formaldehyde and acrolein, which can promote DNA adduct formation and p53 mutation 51,52 , relative to other E-liquids, with a concomitant increase in urinary concentrations of the acrolein metabolite 3-hydroxypropyl mercapturic acid (3-HPMA) 53

[34] Music 1960s Arlo Guthrie uses the slur in his 1967 signature song "Alice's Restaurant", noting it as a potential way to avoid military induction at the time (Guthrie had removed the word from live performances of the song in the 21st century)

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