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Bershady, J

Research suggests that inhaling e-cigarette aerosol may contribute to several conditions that can lead to the development of heart disease, including: Oxidative stress, which is when harmful chemicals damage cells and tissues over time, and inflammation Damage to blood vessel function Changes in the body that can lead to atherosclerosis, a buildup of fatty plaque in the arteries Nicotine adds to cardiovascular strain Nearly all e-cigarettes, pouches and other tobacco products contain natural or synthetic nicotine, a highly addictive chemical that can raise blood pressure and heart rate, narrow blood vessels and force the heart to work harder

James Carville