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Neuropsychiatric effects of caffeine

In some instances, upon administration of a controlled release auris formulation or composition described herein (e.g., a formulation comprising a therapeutic agent), drug concentrations relative to the binding constants of one or more otic receptors are relevant in determining a biologically meaningful PK profile or the minimum concentration of an active agent required for a therapeutic effect

Antiinflammatory & antioxidant effects: Reduces stressrelated pathways

J Med Plants Res 5:33753379 Zeng L, Yang T, Yang K, Yu G, Li J, Xiang W, Chen H (2022) Efficacy and safety of curcumin and curcuma longa extract in the treatment of arthritis: a systematic review and meta-analysis of randomized controlled trial