377 Iron overload, following increased intake, which may in particular result from the use of iron-containing implants widely employed in orthopaedic surgery, 378 or can occur after haemorrhagic stroke, results in compensatory upregulation of glial iron transporters, and down-regulation of neuronal iron transporters, both aimed at neuroprotection
Most studies have involved non-pregnant populations, which makes it challenging to draw definitive conclusions about its safety during pregnancy
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the interaction with growth hormone secretagogues, which may raise glucose, is unpredictable Cardiovascular effects increased heart rate has been observed with GLP-1-based therapies