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Description

J Recept Ligand Channel Res

Since its initial characterization, a central theme that has emerged is that ferroptosis represents a fundamental metabolic vulnerabilityone that arises when antioxidant systems fail to detoxify lipid hydroperoxides (LOOH) 1,8,9

C.HerrB

The RTA calculations with Ser441Leu mutation has undermined the allosteric communications by reducing transmission intensity of the DOFs in-between the rigid allosteric hotspot regions (Fig