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A flow diagram depicting the complete data collection process using PRISMA 35 is available in Fig

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We speculate, that modulating homeostatic balance in microglia, could have promising therapeutic potential in withdrawal, tolerance, and abstinence-related neural adaptations in nicotine addiction, in the adolescent brain

In the European Union, the Tobacco Products Directive (TPD) and ongoing discussions around flavor ban extensions, similar to those already applied to cigarettes and e-cigarettes in certain member states, pose a structural risk to the flavored shisha tobacco segment that could materially impact market growth in one of the world's most important regions