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Interventions that include multiple components, such as the "5-A" approach (Ask, Advise, Assess, Assist and Arrange), have been applied successfully to help pregnant mothers quit smoking

With time and effort, quitting smoking and maintaining a smoke-free lifestyle can become a reality

Furthermore, these neuropeptides act on nonneuronal cells to stimulate the release of additional proinflammatory mediators, including ATP, adenosine, bradykinin, prostaglandins, leukotrienes, histamine, tumor necrosis factor (TNF-), interleukin-1 (IL-1), proteases, and glutamate [121]

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