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Common Side Effects: The most frequently reported side effects in clinical trials were mild and included headache and minor gastrointestinal symptoms

Abstract Many potentially toxic electrophilic xenobiotics and some endogenous compounds are detoxified by conversion to the corresponding glutathione S -conjugate, which is metabolized to the N -acetylcysteine S -conjugate (mercapturate) and excreted

Critics argue that trials supporting CBT and GET are heavily reliant on subjective outcomes (e.g., self-reported fatigue and physical function), resulting in highly inconsistent recovery rates (7%69%) that are determined by arbitrary thresholds

CoQ10 is highly lipophilic with poor aqueous solubility, making conventional oral formulations difficult for the body to absorb