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Once all parameters derived from the thermodynamic cycle shown (Figure 6B) as well as the impact of the cellular buffer and any change in the number of sensor molecules per cell (in high and in low metal) for each metallosensor are considered, response curves centered on K d S that relate fractional transcription output to the intracellular availability of the cognate metal are obtained (Figure 8A)

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It was reported that the TB-500 appeared to accelerate the wound-healing process in all test models, regardless of the stated pre-existing conditions

Smaller infarcts preserve more functional tissue, which translates to better pumping ability and improved long-term outcomes