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10.1016/j.cell.2016.02.035 37 ChenL.ZhangJ.LiC.WangZ.LiJ.ZhaoD.et al

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Vagotomy in animal studies is said to disrupt the transfer of -synuclein derived from the gut to the CNS, but human observational evidence is inconsistent, with some studies indicating no change in PD incidence and others suggesting a reduced risk following truncal vagotomy (Elfil et al., 2020)

Nanoparticles are used to deliver and control drug release and adjust the intracellular chemical reaction to affect the ROS levels, thereby improving the pharmacokinetic properties of the drug [58, 195, 196]