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increased 5OXP was associated with increased biosynthesis whilst OPA production indicated the depletion of the sulfur-containing amino acids essential for GSH biosynthesis.35 Whilst poor nutritional status may predispose some subjects to toxicity via a reduced ability to produce GSH for NAPQI-detoxication other metabolic factors may also come into play

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About the Author: Dr Birgit Schiel, life and social counselling (focus on health), individual diploma studies in health science specialist area: pharmacy, doctorate degree in natural sciences, scientific consultant at Pro Medico

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