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In specific embodiments, auris formulations described herein are formulated to provide a delivered perilymph-suitable osmolarity at the target site of action of about 250 to about 320 mOsm/L and preferably about 270 to about 320 mOsm/L

Vitamin C helps "recharge" spent glutathione molecules, turning them back into their active (reduced) state so they can go back to work

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Each warm-up cycle volatilizes trace amounts of benzyl alcohol and increases oxidation rates