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Benefit #4: Cardiovascular Risk Reduction (Moderate Evidence) Evidence Quality: Animal studies with promising markers Mechanism: Improved lipid profile and reduced inflammation Research indicates 5-amino-1MQ may reduce cardiovascular risk through multiple pathways

Modulation of gene expression and cell membrane signaling

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In an experimental model, transgenic mice expressing a kinase-deficient IGF-1R -subunit (thus displaying reduced signal transduction in both IGF-1R and hybrid receptors) developed diabetes early on life [162, 236]