l carnitine and berberine supplement GLP-1 Booster Supplement, 20-in-1 Akkermansia & Berberine, 60 Capsules Bloom Berberine + L-Carnitine Effervescent

Instead of getting antioxidant protection from both ingredients, you can end up with increased oxidative stress at the skin surface

Drug Des Devel Ther 12:40954105 Daly R, Blackburn G, Best C, Goodyear CS, Mudaliar M, Burgess K, Stirling A, Porter D, McInnes IB, Barrett MP, Dale J (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation

It is important to note that the aforementioned study, while encouraging, does not reach the level of a noninferiority study, a trial in which an experimental treatment is compared with the standard of care, to determine whether the experimental treatment is at least as beneficial as established therapies

Williams et al., 2013