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Preclinical Research: Fat Metabolism and Adiposity Initial animal studies conducted in the early 2000s reported that chronic exposure to AOD-9604 in obese mice and Zucker rats led to reductions in weight gain and increased fat oxidation

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Because this region has been linked to fat metabolism in research models, it is sometimes described as part of a lipolytic domain. In laboratory settings, AOD 9604 is used to explore how growth hormonederived fragments may influence fat breakdown, fat storage, and energy use in cell-based systems and non-clinical animal modelswithout the broader hormonal activity of full-length growth hormone

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