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Human data is still very limited, including small pilot work such as the knee pain survey of 16 patients, plus a few other early studies and reviews calling out the lack of large, rigorous trials

Liver fibrosis progression is governed by bidirectional crosstalk between T cells and hepatic stellate cells (HSCs)

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its strongest evidence base is in cardiac muscle, skeletal muscle, and skin wound healing models The combination is studied to investigate whether the two pathways exhibit additive or synergistic effects across tissue repair endpoints a question that would be difficult to study with either compound alone