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It protects against neural tube defects and increases blood levels of folate

The siRNA-NP targeting diverse molecular mechanisms implicated in Alzheimer's disease, to downregulate genes such as bridging integrator 1 (BIN1), sortilin-related receptor 1 (SORL1), and clusterin (CLU) has proven useful in various animal models (105)

This broad neuroprotective scope of SF includes reduced damage across models of Huntingtons disease, epilepsy, and chemotherapy-induced neuropathy, as well as exposure to carbon monoxide and various environmental toxins as summarized in Table 2

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