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Importantly, targeted delivery of metabolites like butyrate can more successfully restore intestinal homeostasis and reduce inflammatory responses (294)

doi: 10.1021/jf0726942 99 SeeramNPZhangYMcKeeverRHenningSMLeeRPSuchardMAet al

This cellular and molecular damage accelerates the aging process, driving the onset of age-related diseases such as cardiovascular disorders, neurodegenerative diseases, diabetes, and inflammatory conditions

Gilhar A, Landau M, Assy B, Shalaginov R, Serafimovich S, Kalish RS (2001) Melanocyte-associated T cell epitopes can function as autoantigens for transfer of alopecia areata to human scalp explants on Prkdc(scid) mice