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Description

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2.8.2 Calculation of the Quantitative Concentration of First-Order Variables The peak area ratio of a metabolite to that of the isotope internal standard was substituted into the optimal linear equation obtained in the previous step

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Because there were seven randomized trials reporting on more than 500 patients from which to draw evidence (including five trials that compared PPS to placebo, one trial that examined PPS dose-response effects, and one that compared PPS to CyA), the numerous observational studies on PPS were not used

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