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Those same miRNAs also affect tumor suppressor genes.[ref] While a lot more research is needed here, the impact of miRNA on both tumor suppressors and MTHFR may be part of why folate is both beneficial for preventing cancer and then detrimental during some types of cancer

Processing of eggs, milk, and meat Eggs lose 0%, 19%, 239%, 1147%, and 1050% folate, resp., due to poaching, scrambling, boiling, frying, and baking 92,100,102,104,162,329,375,376,382,383,443

Additionally, peptide therapy may not be appropriate for individuals taking immunosuppressant medications or those dealing with active systemic infections, autoimmune disorders, or poorly controlled metabolic conditions

It is inadvisable to give yourself an injection of any sort unless you are fully confident in your ability to inject the drug or supplement safely, and this applies to a B12 injection too