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The cost differential can be substantial, with cyanocobalamin costing roughly one-tenth the price of methylcobalamin in pharmaceutical quantities

Research literature describes benzyl alcohol as an effective preservative used in appropriately formulated multidose products (Johnson et al., 2017)

We recommend using a calibrated thermometer to monitor the internal temperature regularly to ensure it doesnt fluctuate outside this critical range.

If patients are to start NASCOBAL before having tolerated cyanocobalamin parenterally, consider administering an intradermal test dose of parenteral vitamin B12 to patients suspected of cyanocobalamin hypersensitivity [see Dosage and Administration (2.1)]