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Notably, diffuse low grade cytotoxic edema, in contrast to the dense cytotoxic edema associated with ischemic stroke, may lead to more subtle volume loss and perhaps explains the findings noted above associating mild imaging abnormalities with dystonic CP

The goal is not just to produce more collagen but to produce collagen that assembles properly into a strong, tight matrix

Immunophenotyping of the hepatic myeloid cell populations demonstrated a reduction in the numbers of Ly6C + monocytes in the livers of AALF mice, indicating a defect in the recruitment of these cells from the systemic circulation ( Figure 3 )