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Biosafety and horizontal gene transfer The application of engineered live bacteria in liver diseases, from laboratory research to clinical practice, requires the establishment of a corresponding safety guarantee system to balance efficacy and risk, and ultimately achieve safe and effective transformation and application

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If low levels of B 12 remain for a long time, the condition also can lead to irreversible damage to nerve cells, which can cause the following symptoms: numbness and tingling in the hands and feet difficulty walking muscle weakness irritability memory loss dementia depression psychosis