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However, these studies also highlight important challenges in clinical translation, particularly regarding interindividual variability in response and the need for optimized delivery strategies

The intracellular glutamate concentration is nearly 10-fold higher than the Km value, but intracellular cysteine concentrations approximate the apparent Km value [10] indicating that cysteine may be a limiting substrate for GCL

Here, we show that 3-mercaptopyruvate sulfurtransferase (3MST) produces Cys-SSH and GSSH together with the potential signaling molecules hydrogen per- and tri-sulfide (H 2 S 2 and H 2 S 3 )

doi:10.1155/2012/324832 Hussain M, et al