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"Limits of aerobic metabolism in cancer cells"

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At 24 h, the upregulation of HMOX1 and GADD45B remained significant in both cell types, but DNAJB1 regulation declined and was no longer significant in HepG2 ATP7B-KO cells

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sequence is as follows: 5-TAAGACACGATGCGATAAAATCTGTTTGTAAAATTTATTAAGGGTACAAATTGCCCTAGC-3

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However, robust quantitative translation between administered experimental doses and plausible human internal burdens remains highly uncertain due to variability in exposure assessment assumptions, limited size-resolved data on internal PET burdens in humans (particularly for the nanoscale fraction), and methodological constraints in detecting and characterising sub-micrometre particles in complex biological matrices

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