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At higher concentrations, G3 response were not good as compared to G2 concentration

The likely upregulation of melatonin synthesis in stressed mitochondria is also strongly supported by abundant data showing that plant cells exhibit a rapid compensatory upregulated melatonin production when they are exposed to radical-mediated stresses resulting from multiple events, e.g., cold or hot ambient temperatures (97, 98), increased salinity (99) or chemical exposure (100), drought (101), etc

Combined inhibition of class 1-PI3K-alpha and delta isoforms causes senolysis by inducing p21WAF1/CIP1 proteasomal degradation in senescent cells