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One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead) A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation

Proc Natl Acad Sci U S A 106:39415

They are produced by different types of cells and, once released in the body, induce specific reactions in adjacent cells (paracrine effect), in others far away (endocrine effect) or in those that have created them (autocrine effect)

However, their activity consumes significant amounts of NAD + , leading to a depletion of cellular NAD + levels and impacting energy metabolism and cell survival 58