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By injecting subcutaneously near the ankle, the hypothesis is that the peptide can more easily permeate the surrounding tissues and reach the damaged structures

More serious but rare adverse events include pancreatitis (0.2% incidence), gallbladder disease requiring surgical intervention, and medullary thyroid carcinoma risk in genetically predisposed individuals (contraindicated in patients with personal or family history of MTC or MEN2 syndrome)