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Cys 2 ), cystine-free (Cys 2 -free), or cystine-free/GSH-supplemented (750 M) medium for the indicated timepoints, and cell numbers were determined (n = 2 technical replicates representative of one experiment)

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To capture the most recent developments, we conducted a supplementary search extending through the end of 2024, identifying nearly 60 additional DHT-enabled rare disease trials initiated in that year alone