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Researchers associate a vitamin B12 deficiency with various health issues, megaloblastic anemia neurological changes and disorders infertility depression neural tube defects and developmental delays in children born to those with a vitamin B12 deficiency Supplementation may help to reduce the risk of these health issues

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A systematic review of clinical trials found L-carnitine users lost roughly 1-2 kg more than placebo over several months, and evidence for significant performance enhancement is inconsistent