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During the early phase of chronic stress, the HPA axis may be transiently activated, leading to elevated circulating cortisol levels that suppress proinflammatory cytokine production through glucocorticoid receptor-mediated negative feedback (Alotiby, 2024)

Speak to your research supervisor or healthcare provider if: You experience skin reactions at the injection site You have a bleeding disorder or are on anticoagulant therapy You are taking other peptide therapies

59 Chronic symptoms can be treated with betahistine (Serc) (a histamine signaling modulator), available as a compounded preparation in the United States, or diuretics

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