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To further investigate the relative contributions of MOR-expressing enteric versus MOR-expressing PVN Glu neurons in morphine-induced constipation, we infused AAV-DIO-shMOR-EGFP or AAV-DIO-EGFP control virus into the PVN of VgluT2-Cre mice, then induced constipation by i.p

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[5] However, a study involving active men noted very favorable performance effects of GPLC, as well as a significant reduction in blood lactic acid, a byproduct of anaerobic metabolism thought to impair muscle performance