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Designed for researchers investigating advanced cellular pathways, this formulation features 5-Amino-1-methylquinolinium, a potent small molecule inhibitor of the enzyme Nicotinamide N-methyltransferase (NNMT)

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Starting low and escalating gradually produced fewer gastrointestinal side effects than starting directly at a higher dose, which is why the 2mg +2mg-every-4-weeks schedule became the standard escalation approach in the published data

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