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Fibroblasts, the primary producers of collagen in connective tissue, show increased chemotactic movement toward BPC-157-treated sites in in vitro studies, resulting in earlier matrix deposition compared to untreated controls

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Notably, in addition to synoviocytes, synovial macrophages also have an important role in synovial inflammation of OA [137]

coli , this protein was also found in the insoluble fraction, and neither its fusion to thioredoxin, nor to maltose-binding protein, increased its solubility