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Early pharmacology work described it as a selective growth-hormone secretagogue, with GH release and little ACTH or cortisol signal in the foundational studies

Side effects are minimal, typically limited to mild injection site redness

Signs of immune cell activation, including increased numbers of white blood cells, monocytes, memory T cells (CD4 + CD45RA + ), activated T cells (e.g., CD7 + CD25+ and CD2 + HLADR + ), and B cells (CD19 + , CD20 + , and CD21 + ), coupled with an increased CD4 + /CD8+ ratio [24,25,26,27], were detected in various study populations of IMDD patients

Mureddu M, Funck T, Morana G, Rossi A, Ramaglia A, Milanaccio C, Verrico A, Bottoni G, Fiz F, Piccardo AA