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Ethical principles of the study ensured compliance with European Directive 010/63/E, the Law on Amendments to Animal Protection Act (Official Gazette 37/13), the Animal Protection Act (Official Gazette 135/06), Ordinance on the protection of animals used for scientific purposes (Official Gazette 55/13), FELASA recommendations and recommendations of the Ethics Committee School of Medicine, University of Zagreb

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BPC-157 is a stable 15-amino-acid fragment obtained from the protein of human gastric juice, while TB-500 is a synthetic variant of the active domain of Thymosin Beta-4