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130 Leptin signaling involves a receptor located on the cell membrane that initiates downstream signaling pathways, such as the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway, to stimulate energy expenditure while suppressing appetite

Lateral cephalograms of all the patients were taken in natural head position using Planmeca proline XC cephalostat (Finland) with the teeth in centric occlusion and were evaluated according to Hassel and Farman 28 method (Fig

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