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These data suggest that TMAO inhibits cardiac vascular development by reducing Hif-1 protein levels, ultimately exacerbating heart dysfunction in CKD mice (Xie et al., 2022)

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10.3390/molecules26227021 2 AlkhaibariA

Totsuka K, Ueta T, Uchida T, Roggia MF, Nakagawa S, Vavvas DG et al (2018) Oxidative stress induces ferroptotic cell death in retinal pigment epithelial cells