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Reported Reactions Attributed to Each Component BPC-157: The preclinical literature on BPC-157 does not report consistent toxic effects at doses studied in animal models

However, these effects are expected with the procedure rather than specific to the peptide

HUMAN WARNINGS: Children should not come in contact with the application site for 30 minutes after application

The presence of Nrf2 and its inhibitor Keap1 in plasma is associated with damaged vascular endothelial cell-, macrophage-and other cell-associated leakage secondary to the loss of cell membrane integrity due to lipid peroxidation following chronic inflammation and oxidative stress (Kasprzak et al., 2020), and Nrf2 and Keap1 in circulation are markers of severe inflammation and oxidative stress (Tu et al., 2019)