The product of this gene (i.e., GGT-rel) was shown to cleave the -glutamyl bond of LTC 4 (a glutathione S -conjugate) but not the -glutamyl substrates routinely used to assay GGT activity
Here are some other ways to help increase levels of glutathione, along with taking care to optimize vitamin D: limit alcohol consumption decrease exposure to POPs increase intake of other antioxidants to decrease overall oxidative stress increase intake of nutrients that promote glutathione production, such as NAC (N-acetylcysteine), 1000 mg/day, whey, or SAMe get enough magnesium and selenium in the diet, as both are necessary for glutathione production foods such as almonds, cruciferous vegetables, and even alcohol-free beer have been shown to raise glutathione levels, as has meditation
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It was reported that there is a relation between hyperthyroidism and deteriorations of free radicals and antioxidant systems that increase lipid peroxidation and oxidative stress [22]